Equipment & Facilities

Equipment & Facilities

Following is a list of key items of equipment/instrumentation available at the PMBRC.

  • X-ray Diffractometer (XRD), with non-ambient capability – Bruker D8 Advance
  • Particle Size Analyser (Laser Diffraction) – Malvern Instruments Mastersizer 2000 (Liquid & Powder Units)
  • Particle Size Analyser (Dynamic Light Scattering) – Microtrac, Nanotrac Wave II
  • Differential Scanning Calorimeter (DSC) – NETZSCH DSC214 polyma & TA Instruments Q2000
  • Thermal Gravimetric Analyser (TGA) – TA Instruments Q50
  • Surface Tension & Contact Angle Measurement System – Krüss G10
  • Texture Analyser – Stable Micro Systems, TA.XTplus
  • Dynamic Vapour Sorption (DVS) – Surface Measurement Systems, DVS Intrinsic
  • Powder Rheometer – Freeman Technology FT4
  • Fluid Rheometer – TA Instruments ARG2
  • LC/MS System – Agilent 1200 Series / XCT Ultra Ion-Trap MS Detector, with HPLC-Chip
  • LC/MS System – Agilent 1260 Infinity II Series / 6545 LC/Q-TOF MS Detector
  • Rapid Resolution LC Systems – Agilent 1200 Series, with Photodiode Array, Refractive Index and Fluorescence Detection
  • Ion Chromatography System – Thermo Scientific, Dionex ICS-5000
  • Supercritical Fluid Chromatography (SFC) System – Waters, Acuity UPC2 CO2
  • GC/MS System (Ion Trap) – Varian 450-GC / 220-MS, with specialist Programmable Solids Probe, SPME and Headspace Accessories
  • GC/MS System (Single Quadrupole) – Thermo, Focus GC & DSQ MS
  • GC/FID System – Hewlett Packard, 6890 Series
  • Capillary Electrophoresis (CE) System – Agilent CE G1600AX
  • 400 MHz NMR System, including Solid State Probe – Joel ECX-400
  • FTIR Spectrometer, with Microscope – Varian 660-IR & 610-IR
  • FTIR Spectrometer, with UATR Accessory – PerkinElmer Spectrum Two FT-IR Spectrometer
  • NIR Spectrometer – ThermoScientific ANTARIS II FT-NIR Analyser
  • ICP-Optical Emission Spectrometer – Varian 710-ES
  • UV Spectrometer – Shimadzu UV-2401PC
  • Fluorescence Spectrometer – Varian CARY Eclipse
  • Ultra-Low Light Level Spectrometer – Princeton Instruments
  • Benchtop Scanning Electron Microscope (SEM), with Energy Dispersive X-ray Spectroscopy (EDX) – TM4000 Hitachi Technologies
  • Benchtop Scanning Electron Microscope (SEM), with Energy Dispersive X-ray Spectroscopy (EDX) – TM4000 Hitachi Technologies
  • Atomic Force Microscope (AFM) – Bruker Dimension Icon (Glovebox mounted), with the following modes: Contact (liquid/ambient), Tapping (liquid/ambient), Peak Force, Torsional Resonance AFM, Peak Force Kelvin Probe, Peak Force Tunnelling, Tunnelling AFM, Peak Force Quantitative Nanomechanical Mapping, Conductive AFM, Photoconductive AFM, Scanning Tunnelling Microscopy (STM)
  • Fluorescence Microscope – Olympus BX51
  • Optical Microscopy – Wide range of optical microscopes available at the PMBRC
  • Spray Dryer – ProCepT 4M8-TriX
  • Fluid Bed Processing (Drying/Granulating/Coating) – GEA Strea 1 Classic
  • Rotary Tablet Press – Riva Piccola 8-station, D-type Tooling
  • Manual Tablet Press – GlobePharma MTCM-I
  • Freeze Dryer – LABCONCO, Freezone 2.5
  • Dissolution Bath – (1.) Distek Dissolution System 2100C; (2.) Vankel/Varian Systems
  • Disintegration Bath – PharmaTest, Dist 3
  • Hardness, Bulk/Tap Density and Friability Testers
  • Polymer Twin-Screw Extrusion System (with Supercritical CO2 Capability) – SCF Processing Ltd.
  • Y-Blender – ERWEKA AR 403, with Y5 Mixing Vessel
  • Protein Analysis System – (1.) iBind2 Western Blotting; (2.) Bolt & Novex native PAGE Electrophoresis Systems
  • Real-Time PCR System – Applied Biosystems 7300
  • Pulsed Field Gel Electrophoresis (PFGE) System – BioRad CHEF-DR II
  • UV-Vis Spectrophotometer (220-750nm) – Nanodrop ND-1000
  • Thermal Cyclers – Applied Biosystems 2720
  • Roche Hybridisation Oven
  • Syngene GeneGenius Bioimaging System
  • Flow Cytometer – Beckman Coulter Cytomics FC 500
  • Suspension Multi-Array System – BIO-RAD Bio-Plex 200
  • Enzyme-Linked ImmunoSorbent Assay (ELISA)
  • Haematology Analyser – Beckman Coulter Ac.T diff
  • Clinical Chemistry Analyser
  • HTS Plate Reader – MSD Model 1250 Sector Imager
  • Environmental Chamber (Temp & RH) – Memmert HPP 110
  • Ovens – Memmert UF260
  • Microwave Digester – CEM, MARS 6
  • Karl Fischer (Water Determination) – Metrohm 701 KF Titrino & 703 Ti Stand
  • Rotary Pumped Coater (Sputtering & Carbon Coating) – Quorum Q150R ES plus
  • Aerosol Jet Printer – Optomec AJ300
  • Nanolithography System – Eulitha PHABLE
  • Thin Film Vacuum Coating System – Edwards AUTO 306
  • Plasmonic Sensor Characterisation Suite – Hamamatsu Opto-Spectrum Generator (OSG); ANDOR ICON charge-coupled device (ccd) camera; ANDOR complementary metal-oxide semiconductor (CMOS) camera
  • Spin-coater – Laurell WS 400B